Investors who focus on long-term opportunities in the stock market look for well-established companies that are already profitable and have a track record of revenue growth. Two wildly different healthcare companies that both fit that description are Vertex Pharmaceuticals (NASDAQ: VRTX) and (NYSE: MDT).

Vertex, a biopharmaceutical company founded in 1989, has improved annual revenue by 636% over the past decade. While it might be difficult for the biotech to continue that pace, its pipeline has the potential to easily drive growth for another decade. 

Medtronic is a medical device company founded in 1949. Because of its large size, with more than 90,000 employees in 150 countries, it has seen less-meteoric annual revenue growth over the past 10 years -- roughly 83%.

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Source Fool.com