Many new businesses don't even last five years. Few get beyond a decade, and only the best of them -- typically those that have built solid economic moats and can continue improving their financial results -- make it to the 20-year mark.

Corporations of this type exist on the market and are sometimes relatively easy to pick out. Let's consider two examples: HCA Healthcare (NYSE: HCA) and (NASDAQ: NFLX). Here's why investing $500 in either stock and holding for the next two decades isn't that hard a call for long-term investors.

Few industries are as certain to remain relevant in the next 20 years as healthcare. And those companies that provide much-needed facilities where patients receive routine treatment, undergo surgical procedures, or are rushed to in emergencies won't go out of style, either.

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Source Fool.com