Berkshire Hathaway (NYSE: BRK.A) (NYSE: BRK.B) CEO Warren Buffett knows how to create piles of money. The stock has increased 4,400,000% since 1965, when Buffett took over the reins. Much of those gains were the result of Buffett's knack for spotting long-term winners either through the stock market or buying companies outright.

At the end of the second quarter, Berkshire's stock portfolio totaled $285 billion. Let's look at two holdings that offer attractive upside potential over the next five years.

Amazon (NASDAQ: AMZN) is a disruptive force in the retail sector. It has more than 200 million Prime members, 627 million square feet of fulfillment space and data centers, and growing revenue streams from lucrative businesses like advertising solutions and cloud services.

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Source Fool.com