Why Nabriva Therapeutics PLC Is Skyrocketing
Investors in Nabriva Therapeutics (NASDAQ: NBRV) are having a wonderful start to the trading week. Shares of the clinical-stage biotech focused on antibiotics rose 36% as of 11:30 a.m. EDT on Monday in response to reporting encouraging data from its phase 3 LEAP 1 trial.
The LEAP 1 trial was designed to study the safety and efficacy of the company's lead compound lefamulin in treating community-acquired bacterial pneumonia (CABP). CABP is leading cause of death from infection in the United States and is a very serious public health issue.
Top-line data from the 551 patient trial showed that lefamulin was able to meet the FDA's and European Medicines Agencies primary endpoints of non-inferiority when compared to moxifloxacin with or without adjunctive linezolid. Specifically, the early clinical response rate assessed for lefamulin was 87.3%, while moxifloxacin's rate was 90.2%. What's more, lefamulin's safety data was also comparable to moxifloxacin.
Source: Fool.com
